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1

Glutamine: pleiotropic roles in tumor growth and stress resistance

Naval P. Shanware, Andrew R. Mullen, Ralph J. DeBerardinis, Robert T. Abraham

Journal:

Journal of Molecular Medicine

Year:

2011

Language:

english

File:

PDF, 683 KB

english, 2011

2

The Biology of Cancer: Metabolic Reprogramming Fuels Cell Growth and Proliferation

Ralph J. DeBerardinis, Julian J. Lum, Georgia Hatzivassiliou, Craig B. Thompson

Journal:

Cell Metabolism

Year:

2008

Language:

english

File:

PDF, 949 KB

english, 2008

3

Understanding the Intersections between Metabolism and Cancer Biology

Vander Heiden, Matthew G., DeBerardinis, Ralph J.

Journal:

Year:

2017

Language:

english

File:

PDF, 1.21 MB

english, 2017

4

Tumor Microenvironment, Metabolism, and Immunotherapy

Phimister, Elizabeth G., DeBerardinis, Ralph J.

Journal:

New England Journal of Medicine

Year:

2020

Language:

english

File:

PDF, 388 KB

english, 2020

5

The Distinct Metabolic Profile of Hematopoietic Stem Cells Reflects Their Location in a Hypoxic Niche

Tugba Simsek, Fatih Kocabas, Junke Zheng, Ralph J. DeBerardinis, Ahmed I. Mahmoud, Eric N. Olson, Jay W. Schneider, Cheng Cheng Zhang, Hesham A. Sadek

Journal:

Year:

2010

Language:

english

File:

PDF, 1.37 MB

english, 2010

6

Reductive carboxylation supports growth in tumour cells with defective mitochondria

Mullen, Andrew R., Wheaton, William W., Jin, Eunsook S., Chen, Pei-Hsuan, Sullivan, Lucas B., Cheng, Tzuling, Yang, Youfeng, Linehan, W. Marston, Chandel, Navdeep S., DeBerardinis, Ralph J.

Journal:

Year:

2011

Language:

english

File:

PDF, 601 KB

english, 2011

7

2-hydroxyglutarate detection by magnetic resonance spectroscopy in IDH-mutated patients with gliomas

Choi, Changho, Ganji, Sandeep K, DeBerardinis, Ralph J, Hatanpaa, Kimmo J, Rakheja, Dinesh, Kovacs, Zoltan, Yang, Xiao-Li, Mashimo, Tomoyuki, Raisanen, Jack M, Marin-Valencia, Isaac, Pascual, Juan M,

Journal:

Nature Medicine

Year:

2012

Language:

english

File:

PDF, 950 KB

english, 2012

8

A nanoparticle-based strategy for the imaging of a broad range of tumours by nonlinear amplification of microenvironment signals

Wang, Yiguang, Zhou, Kejin, Huang, Gang, Hensley, Christopher, Huang, Xiaonan, Ma, Xinpeng, Zhao, Tian, Sumer, Baran D., DeBerardinis, Ralph J., Gao, Jinming

Journal:

Nature Materials

Year:

2013

Language:

english

File:

PDF, 1.50 MB

english, 2013

9

A Role for the Mitochondrial Pyruvate Carrier as a Repressor of the Warburg Effect and Colon Cancer Cell Growth

Schell, John C., Olson, Kristofor A., Jiang, Lei, Hawkins, Amy J., Van Vranken, Jonathan G., Xie, Jianxin, Egnatchik, Robert A., Earl, Espen G., DeBerardinis, Ralph J., Rutter, Jared

Journal:

Year:

2014

Language:

english

File:

PDF, 2.65 MB

english, 2014

10

Metabolic pathways promoting cancer cell survival and growth

Boroughs, Lindsey K., DeBerardinis, Ralph J.

Journal:

Nature Cell Biology

Year:

2015

Language:

english

File:

PDF, 554 KB

english, 2015

11

Oxidative stress inhibits distant metastasis by human melanoma cells

Piskounova, Elena, Agathocleous, Michalis, Murphy, Malea M., Hu, Zeping, Huddlestun, Sara E., Zhao, Zhiyu, Leitch, A. Marilyn, Johnson, Timothy M., DeBerardinis, Ralph J., Morrison, Sean J.

Journal:

Year:

2015

Language:

english

File:

PDF, 10.06 MB

english, 2015

12

Lkb1 deficiency confers glutamine dependency in polycystic kidney disease

Flowers, Ebony M., Sudderth, Jessica, Zacharias, Lauren, Mernaugh, Glenda, Zent, Roy, DeBerardinis, Ralph J., Carroll, Thomas J.

Journal:

Nature Communications

Year:

2018

Language:

english

File:

PDF, 2.53 MB

english, 2018

13

Metabolic regulation of transcription through compartmentalized NAD + biosynthesis

Ryu, Keun Woo, Nandu, Tulip, Kim, Jiyeon, Challa, Sridevi, DeBerardinis, Ralph J., Kraus, W. Lee

Journal:

Year:

2018

Language:

english

File:

PDF, 1.69 MB

english, 2018

14

Metabolic reprogramming and cancer progression

Faubert, Brandon, Solmonson, Ashley, DeBerardinis, Ralph J.

Journal:

Year:

2020

File:

PDF, 2.28 MB

2020

15

N-Acetyl Cysteine Abrogates Silver-Induced Reactive Oxygen Species in Human Cells Without Altering Silver-based Antimicrobial Activity

Shah, Kush N., Shah, Parth N., Mullen, Andrew R., Chen, Qingquan, Southerland, Marie R., Chirra, Bhagath, DeBerardinis, Ralph J., Cannon, Carolyn L.

Journal:

Toxicology Letters

Year:

2020

File:

PDF, 4.34 MB

2020

16

Myoclonus in a patient with a deletion of the ε-sarcoglycan locus on chromosome 7q21

Ralph J. DeBerardinis, Danielle Conforto, Karen Russell, Jennifer Kaplan, Peter R. Kollros, Elaine H. Zackai, Beverly S. Emanuel

Journal:

American Journal of Medical Genetics Part A

Year:

2003

Language:

english

File:

PDF, 168 KB

english, 2003

17

DiGeorge anomaly in a patient with isochromosome 18p born to a diabetic mother

Ralph J. DeBerardinis, Livija Medne, Nancy B. Spinner, Elaine H. Zackai

Journal:

American Journal of Medical Genetics Part A

Year:

2005

Language:

english

File:

PDF, 150 KB

english, 2005

18

Measurement of glycine in the human brain in vivo by 1H-MRS at 3 T: application in brain tumors

Changho Choi, Sandeep K. Ganji, Ralph J. DeBerardinis, Ivan E. Dimitrov, Juan M. Pascual, Robert Bachoo, Bruce E. Mickey, Craig R. Malloy, Elizabeth A. Maher

Journal:

Magnetic Resonance in Medicine

Year:

2011

Language:

english

File:

PDF, 1.68 MB

english, 2011

19

Isocitrate dehydrogenase 1/2 mutational analyses and 2-hydroxyglutarate measurements in Wilms tumors

Dinesh Rakheja, Midori Mitui, Richard L. Boriack, Ralph J. DeBerardinis

Journal:

Pediatric Blood & Cancer

Year:

2011

Language:

english

File:

PDF, 96 KB

english, 2011

20

10.1038/3104

Kazazian, Haig H., DeBerardinis, Ralph J., Goodier, John L., Ostertag, Eric M.

Journal:

Nature Genetics

Year:

1998

Language:

english

File:

PDF, 100 KB

english, 1998

21

Many human L1 elements are capable of retrotransposition

Sassaman, Donna M., Dombroski, Beth A., Moran, John V., Kimberland, Michelle L., Naas, Thierry P., DeBerardinis, Ralph J., Gabriel, Abram, Swergold, Gary D., Kazazian, Haig H.

Journal:

Nature Genetics

Year:

1997

File:

PDF, 814 KB

1997

22

A mouse model of human L1 retrotransposition

Ostertag, Eric M., DeBerardinis, Ralph J., Goodier, John L., Zhang, Yue, Yang, Nuo, Gerton, George L., Kazazian, Haig H.

Journal:

Nature Genetics

Year:

2002

Language:

english

File:

PDF, 700 KB

english, 2002

23

Autophagy in metazoans: cell survival in the land of plenty

Lum, Julian J., DeBerardinis, Ralph J., Thompson, Craig B.

Journal:

Nature Reviews Molecular Cell Biology

Year:

2005

Language:

english

File:

PDF, 522 KB

english, 2005

24

The glucose dependence of Akt-transformed cells can be reversed by pharmacologic activation of fatty acid β-oxidation

Buzzai, Monica, Bauer, Daniel E, Jones, Russell G, DeBerardinis, Ralph J, Hatzivassiliou, Georgia, Elstrom, Rebecca L, Thompson, Craig B

Journal:

Year:

2005

Language:

english

File:

PDF, 377 KB

english, 2005

25

Comparison of kinetic models for analysis of pyruvate-to-lactate exchange by hyperpolarized 13C NMR

Crystal Harrison, Chendong Yang, Ashish Jindal, Ralph J. DeBerardinis, M. A. Hooshyar, Matthew Merritt, A. Dean Sherry, Craig R. Malloy

Journal:

NMR in Biomedicine

Year:

2012

Language:

english

File:

PDF, 1.02 MB

english, 2012

26

Full-Length L1 Elements Have Arisen Recently in the Same 1-kb Region of the Gorilla and Human Genomes

DeBerardinis, Ralph J., Kazazian, Jr., Haig H.

Journal:

Journal of Molecular Evolution

Year:

1998

Language:

english

File:

PDF, 617 KB

english, 1998

27

Cancer metabolism: When more is less

Jiang, Lei, DeBerardinis, Ralph J.

Journal:

Year:

2012

Language:

english

File:

PDF, 229 KB

english, 2012

28

Analysis of the Promoter from an Expanding Mouse Retrotransposon Subfamily

Ralph J. DeBerardinis, Haig H. Kazazian Jr.

Journal:

Year:

1999

Language:

english

File:

PDF, 121 KB

english, 1999

29

Cellular Metabolism and Disease: What Do Metabolic Outliers Teach Us?

Ralph J. DeBerardinis, Craig B. Thompson

Journal:

Year:

2012

Language:

english

File:

PDF, 934 KB

english, 2012

30

Serine Metabolism: Some Tumors Take the Road Less Traveled

Ralph J. DeBerardinis

Journal:

Cell Metabolism

Year:

2011

Language:

english

File:

PDF, 225 KB

english, 2011

31

Brick by brick: metabolism and tumor cell growth

Ralph J DeBerardinis, Nabil Sayed, Dara Ditsworth, Craig B Thompson

Journal:

Current Opinion in Genetics & Development

Year:

2008

Language:

english

File:

PDF, 767 KB

english, 2008

32

High Frequency Retrotransposition in Cultured Mammalian Cells

John V Moran, Susan E Holmes, Thierry P Naas, Ralph J DeBerardinis, Jef D Boeke, Haig H Kazazian Jr.

Journal:

Year:

1996

Language:

english

File:

PDF, 351 KB

english, 1996

33

Genetically-defined metabolic reprogramming in cancer

Andrew R. Mullen, Ralph J. DeBerardinis

Journal:

Trends in Endocrinology & Metabolism

Year:

2012

Language:

english

File:

PDF, 446 KB

english, 2012

34

A Mitochondrial Power Play in Lymphoma

Ralph J. DeBerardinis

Journal:

Year:

2012

Language:

english

File:

PDF, 162 KB

english, 2012

35

The Hypoxic Epicardial and Subepicardial Microenvironment

Fatih Kocabas, Ahmed I. Mahmoud, Drazen Sosic, Enzo R. Porrello, Rui Chen, Joseph A. Garcia, Ralph J. DeBerardinis, Hesham A. Sadek

Journal:

Journal of Cardiovascular Translational Research

Year:

2012

Language:

english

File:

PDF, 824 KB

english, 2012

36

Erratum to: The Hypoxic Epicardial and Subepicardial Microenvironment

Fatih Kocabas, Ahmed I. Mahmoud, Drazen Sosic, Enzo R. Porrello, Rui Chen, Joseph A. Garcia, Ralph J. DeBerardinis, Hesham A. Sadek

Journal:

Journal of Cardiovascular Translational Research

Year:

2012

Language:

english

File:

PDF, 47 KB

english, 2012

37

The G Protein-Coupled Taste Receptor T1R1/T1R3 Regulates mTORC1 and Autophagy

Wauson, Eric M., Zaganjor, Elma, Lee, A-Young, Guerra, Marcy L., Ghosh, Anwesha B., Bookout, Angie L., Chambers, Chris P., Jivan, Arif, McGlynn, Kathleen, Hutchison, Michele R., Deberardinis, Ralph J.

Journal:

Year:

2012

Language:

english

File:

PDF, 2.51 MB

english, 2012

38

The Proto-oncometabolite Fumarate Binds Glutathione to Amplify ROS-Dependent Signaling

Sullivan, Lucas B., Martinez-Garcia, Eva, Nguyen, Hien, Mullen, Andrew R., Dufour, Eric, Sudarshan, Sunil, Licht, Jonathan D., Deberardinis, Ralph J., Chandel, Navdeep S.

Journal:

Year:

2013

Language:

english

File:

PDF, 1.12 MB

english, 2013

39

Wilms Tumor in a Child with L-2-hydroxyglutaric Aciduria

Rogers, Robert E., DeBerardinis, Ralph J., Klesse, Laura J., Boriack, Richard L., Margraf, Linda R., Rakheja, Dinesh

Journal:

Pediatric and Developmental Pathology

Year:

2010

Language:

english

File:

PDF, 392 KB

english, 2010

40

Hydrophilic interaction liquid chromatography coupled with MS/MS to detect and quantify dicarboxyethyl glutathione, a metabolic biomarker of the fumarate hydratase deficient cancer cell

Nguyen, Hien P., Chandel, Navdeep S., DeBerardinis, Ralph J., Schug, Kevin A.

Journal:

Journal of Separation Science

Year:

2013

Language:

english

File:

PDF, 404 KB

english, 2013

41

Analysis of Cancer Metabolism by Imaging Hyperpolarized Nuclei: Prospects for Translation to Clinical Research

Kurhanewicz, John, Vigneron, Daniel B., Brindle, Kevin, Chekmenev, Eduard Y., Comment, Arnaud, Cunningham, Charles H., DeBerardinis, Ralph J., Green, Gary G., Leach, Martin O., Rajan, Sunder S., Rizi,

Journal:

Year:

2011

Language:

english

File:

PDF, 1.05 MB

english, 2011

42

The Proto-oncometabolite Fumarate Binds Glutathione to Amplify ROS-Dependent Signaling

Sullivan, Lucas B., Martinez-Garcia, Eva, Nguyen, Hien, Mullen, Andrew R., Dufour, Eric, Sudarshan, Sunil, Licht, Jonathan D., Deberardinis, Ralph J., Chandel, Navdeep S.

Journal:

Year:

2013

File:

PDF, 57 KB

2013

43

A Mitochondrial RNAi Screen Defines Cellular Bioenergetic Determinants and Identifies an Adenylate Kinase as a Key Regulator of ATP Levels

Lanning, Nathan J., Looyenga, Brendan D., Kauffman, Audra L., Niemi, Natalie M., Sudderth, Jessica, DeBerardinis, Ralph J., MacKeigan, Jeffrey P.

Journal:

Year:

2014

Language:

english

File:

PDF, 3.79 MB

english, 2014

44

Penicillamine Therapy for Pediatric Cystinuria: Experience From a Cohort of American Children

DeBerardinis, Ralph J., Coughlin, Curtis R., Kaplan, Paige

Journal:

The Journal of Urology

Year:

2008

Language:

english

File:

PDF, 81 KB

english, 2008

45

Metabolic diversity in human non-small cell lung cancer

Chen, Pei-Hsuan, Cai, Ling, Kim, Hyun, Britt, Rebecca, Xiao, Guanghua, White, Michael A, Minna, John D, DeBerardinis, Ralph J

Journal:

Cancer & Metabolism

Year:

2014

Language:

english

File:

PDF, 77 KB

english, 2014

46

Pyruvate dehydrogenase activity is required for optimal growth under lipid deficient conditions

Rajagopalan, Kartik, DeBerardinis, Ralph

Journal:

Cancer & Metabolism

Year:

2014

Language:

english

File:

PDF, 79 KB

english, 2014

47

Metabolic heterogeneity in cancer

DeBerardinis, Ralph J

Journal:

Cancer & Metabolism

Year:

2014

Language:

english

File:

PDF, 80 KB

english, 2014

48

Reductive carboxylation mediated oxidative stress defense supports anchorage independent cell growth

Jiang, Lei, Mitsche, Matthew, Deberardinis, Ralph, Smans, Karine

Journal:

Cancer & Metabolism

Year:

2014

Language:

english

File:

PDF, 93 KB

english, 2014

49

Identifying metabolomic features that predict metastasis of melanoma from a primary site

Shi, Xiaolei, Hu, Zeping, Piskounova, Elena, Agathocleous, Michalis, Morrison, Sean, DeBerardinis, Ralph

Journal:

Cancer & Metabolism

Year:

2014

Language:

english

File:

PDF, 77 KB

english, 2014

50

Q&A: Targeting metabolism to diagnose and treat cancer

DeBerardinis, Ralph J

Journal:

Cancer & Metabolism

Year:

2014

Language:

english

File:

PDF, 120 KB

english, 2014

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